Author

Francesco Casanova

University of ExeterORCID 0000-0003-0275-4765Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Research Focus:GWAS / association mapping· 2 Assay:GWAS summary statistics· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Jessica TyrrelliD· 2 shared Alexandra C. GillettiD· 1 shared Andrew R. WoodiD· 1 shared Anna MurrayiD· 1 shared Ben West· 1 shared Cathryn M. LewisiD· 1 shared Cecilia M. LindgreniD· 1 shared Chris Wai Hang LoiD· 1 shared

Activity by Year

2017-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersGenetic & Genomic Medicine

Jessica TyrrellORCID

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2 papers

Recent·Most cited

Genetic & Genomic MedicinemedRxivPreprintMar 17, 2026

Clustering of major depressive disorder genetic instruments identifies distinct and directionally opposing effects on cardiometabolic risk

Dale Handley, Renu Bala, Francesco Casanova…·Jessica Tyrrell

This study uses MR-Clust to identify three MDD genetic clusters with opposing effects on T2D and cardiometabolic risk, linking them to distinct biological pathways and depression subtypes.

DOI 10.64898/2026.03.16.26347391

humanGWAS summary statistics

𝕏 PostBluesky

GeneticsbioRxivPreprintNov 6, 2017

A common allele in FGF21 associated with preference for sugar consumption lowers body fat in the lower body and increases blood pressure

Timothy M. Frayling, Robin N. Beaumont, Samuel E. Jones…·Andrew R. Wood

A common FGF21 allele is associated with lower body fat in the lower body, higher blood pressure, and increased carbohydrate intake in a large human cohort.

3 citations

humanGWAS summary statistics

𝕏 PostBluesky