Author

Kirsten Lacombe

University of WashingtonORCID 0000-0003-0299-9447Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:database / resource· 1 Assay:proteomics· 1 Organism:virus· 1

Frequent Co-Authors

Caroline KikawaiD· 3 shared Derek J. SmithiD· 3 shared Janet A. EnglundiD· 3 shared Jesse D. BloomiD· 3 shared John HuddlestoniD· 3 shared Alexander L. GreningeriD· 2 shared Andrea N. LoesiD· 2 shared Benjamin John CowlingiD· 2 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersMicrobiology

Caroline KikawaORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

MicrobiologybioRxivPreprintSep 21, 2026

Near real-time data on the human neutralizing antibody landscape to influenza virus in summer of 2026 shows antigenic advance of H3N2 subclade K region D mutants and H1N1 D.3.1.1 Sa mutants

Caroline Kikawa, Andrew Butler, John Huddleston…·Jesse D. Bloom

This study reports neutralization titers from 355 human sera against 148 influenza strains, showing reduced neutralization of new H3N2 and H1N1 variants.

1 citation

humanbulk RNA-seq

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MicrobiologyVirus EvolutionPeer-reviewedJan 1, 2026

✦ In-depth digest

Near real-time data on the human neutralizing antibody landscape to influenza virus as of early 2026 to inform vaccine-strain selection

Caroline Kikawa, John Huddleston, Samuel A. Turner…·Jesse D. Bloom

Sequencing-based neutralization of 91 H3N2 and H1N1 hemagglutinins against 302 human sera (27,409 titers) shows reduced titers to H3N2 subclade K and H1N1 D.3.1.1.

4 citationstop 1%

humanvirus

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MicrobiologyVirus EvolutionPeer-reviewedJan 1, 2025

Near real-time data on the human neutralizing antibody landscape to influenza virus to inform vaccine-strain selection in September 2025

Caroline Kikawa, John Huddleston, Andrea N. Loes…·Jesse D. Bloom

The paper quantifies neutralizing antibody responses to influenza strains using sera collected in 2024-2025 to inform vaccine-strain selection for 2025.

9 citationstop 3%

humanproteomics

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