Pharmacology & ToxicologybioRxivPreprint
Triptans reprogram Schwann cells to drive medication-overuse headache via β-glycan/TGF-β3 signaling
Martina Chieca, Matilde Marini, Marta Baragli…·Francesco De Logu
This study identifies Schwann cell 5-HT1B/D signaling as a dual mediator of triptan efficacy and medication-overuse headache via TGF-β3-driven proalgesic pathways.
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