Author

Philip Coffino

Rockefeller UniversityORCID 0000-0003-0344-5083Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:perturbation response prediction· 1

Frequent Co-Authors

Barbara A. LyonsiD· 1 shared Bassem ShebliD· 1 shared Denise NgiD· 1 shared Mahsa ShiraniiD· 1 shared Michael D. TomasiniiD· 1 shared Ronaldo Shaquille BowieiD· 1 shared Ruth HookiD· 1 shared Sanford M. SimoniD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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1 shared paperCancer Biology

Barbara A. LyonsORCID

Mutual co-authors in cluster

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1 paper

Recent·Most cited

Specific degrader for fusion oncokinase kills tumors and is augmented by bimodal degrader-siRNA

Mahsa Shirani, Ronaldo Shaquille Bowie, Michael D. Tomasini, Ruth Hook, Denise Ng, Bassem Shebl, Barbara A. Lyons, Philip Coffino, Sanford M. Simon

The paper develops a degrader that specifically targets oncogenic fusions in cancer cells, showing efficacy in preclinical models and enhanced therapeutic effect when combined with siRNA.

bioRxiv · Apr 24, 2025 · PreprintCancer Biology