Decoding protein glycosylation by an integrative mass spectrometry-based de novo sequencing strategy
Jing Gao, Hong‐Xu Chen, Hongrui Yin, Xin Chen, Zhicheng Yang, Yuqiu Wang, Jianhong Wu, Yinping Tian, Hong Shao, Liuqing Wen, Hu Zhou
This paper develops a mass spectrometry-based method to decode glycoproteins by integrating deglycosylation and glycosylation site characterization, enabling accurate sequencing of complex glycosylated proteins.
JACS Au · Jan 22, 2025Peer-reviewedBiochemistry