Loss-of-function of OTUD7A in the schizophrenia-associated 15q13.3 deletion impairs synapse development and function in human neurons
Alena Kozlova, Siwei Zhang, Alex Kotlar, Brendan Jamison, Hanwen Zhang, Serena Qinyun Z. Shi, Marc P. Forrest, John McDaid, David J. Cutler, Michael P. Epstein, Michael E. Zwick, Zhiping P. Pang, Alan R. Sanders, Stephen T. Warren, Pablo V. Gejman, , Jubao Duan
The paper identifies OTUD7A loss-of-function mutations in schizophrenia-associated 15q13.3 deletions and shows they impair synapse development and function in human neurons.
The American Journal of Human Genetics · Aug 1, 2022Peer-reviewedNeuroscience