Author

Tinghua Huang

Yangtze UniversityORCID 0000-0003-0387-9834Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Research Focus:gene regulatory network inference· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:database / resource· 2 Research Focus:benchmarking· 1 Assay:ChIP-seq· 1 Approach:experimental assay· 1

Frequent Co-Authors

Min YaoiD· 3 shared Xuejun GaoiD· 2 shared Binyu WangiD· 1 shared Cheng YuaniD· 1 shared Hao HeiD· 1 shared Hong XiaoiD· 1 shared Jinhui LiuiD· 1 shared Jun YangiD· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersBioinformatics

Min YaoORCID

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3 papers

Recent·Most cited

BioinformaticsbioRxivPreprintOct 2, 2022

Flaver: mining transcription factors in genome-wide transcriptome profiling data using weighted rank correlation statistics

Tinghua Huang, Xinmiao Huang, Binyu Wang…·Xuejun Gao

Flaver identifies key transcription factors in ranked gene-lists using weighted rank correlation, outperforming GSEA in 14% of cases and showing experimental support.

DOI 10.1101/2022.10.02.510575

bulk RNA-seqstatistical model

𝕏 PostBluesky

BioinformaticsPLoS Computational BiologyPeer-reviewedJun 7, 2022

Identification of upstream transcription factor binding sites in orthologous genes using mixed Student's t-test statistics

Tinghua Huang, Hong Xiao, Qi Tian…·Min Yao

This paper introduces a tool called Grit for identifying transcription factor binding sites using a mixed Student's t-test method, showing improved performance over existing tools on ChIP-Atlas datasets.

7 citations

humanChIP-seq

𝕏 PostBluesky

GenomicsbioRxivPreprintJul 24, 2019

Identification of porcine RUNX1 as an LPS-dependent gene expression regulator in PBMCs by Super deepSAGE sequencing of multiple tissues

Tinghua Huang, Min Yang, Kaihui Dong…·Min Yao

DOI 10.1101/713206

bulk RNA-seqstatistical model

𝕏 PostBluesky