Author

Debayani Chakraborty

Indian Institute of Science BangaloreORCID 0000-0003-0403-0162Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biophysics· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:host-pathogen & immune response· 2 Approach:biophysical modeling· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Rahul RoyiD· 2 shared Achinta SannigrahiiD· 1 shared Achinta SannigrahiiD· 1 shared Arijit Patra· 1 shared Avijeet KulshresthaiD· 1 shared D. Thakkar· 1 shared Debarati ChakrabortyiD· 1 shared Dibyajyoti MaityiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersBiophysics

Rahul RoyORCID

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2 papers

Recent·Most cited

BiophysicsbioRxivPreprintJan 28, 2026

Sphingomyelin-Cholesterol Synergy as a Lipid Chaperone Driving Cytolysin A Pore Formation

Achinta Sannigrahi, Debayani Chakraborty, Rimjhim Moral…·Rahul Roy

This study shows that host sphingomyelin and cholesterol act as a lipid chaperone to facilitate the conformational changes of the bacterial toxin Cytolysin A, enabling pore formation.

DOI 10.64898/2026.01.27.702101

biophysical modelinghost-pathogen & immune response

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Cell BiologybioRxivPreprintMay 31, 2025

Membrane Fusion Inhibition, Immune Modulation, and Cholesterol Synthesis Dysregulation During Dengue Virus Inhibition by 25-Hydroxycholesterol

Debayani Chakraborty, Achinta Sannigrahi, Mahammed Kaif…·Rahul Roy

This study shows 25-hydroxycholesterol inhibits dengue virus by disrupting membrane fusion, modulating cholesterol metabolism, and enhancing innate immunity.

1 citation

proteomicsstatistical model

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