YAP/TAZ create a physical niche for the maintenance of adult neural stem cell quiescence
Laura Blasco-Chamarro, Pau García-Bolufer, Pere Duart-Abadía, Antonio Jordán‐Pla, Ma Salomé Sirerol-Piquer, Pau Carrillo-Barberà, Chiara Sgattoni, Isabel Mateos-White, Cristina Gil, José Manuel Morante‐Redolat, Isabel Fariñas
The paper shows that BMP4-induced ECM secretion by quiescent NSCs triggers YAP/TAZ to maintain quiescence through fractone preservation.
bioRxiv · Jun 27, 2025 · PreprintNeuroscience