Isabel Fariñas

This study identifies Polo-like kinase 1 (Plk1) as a regulator of adult neural stem cell quiescence and activation, showing that its inhibition enhances neurogenesis.

This study compares two strategies for combining biologically replicated long-read RNA-seq data to identify transcripts, finding that 'Join & Call' is better for novel isoforms while 'Call & Join' is more efficient for large datasets.

The paper shows that BMP4-induced ECM secretion by quiescent NSCs triggers YAP/TAZ to maintain quiescence through fractone preservation.

This study identifies P2Y13 as a key regulator of NSC activation and division mode in the adult SEZ, distinguishing quiescent from activated NSCs and influencing self-renewal versus differentiation.

This study identifies Kidins220 as critical for NSC survival and adult neurogenesis by regulating AKT and GSK3 activity in response to growth factors.

This study shows p27 represses SOX2 and its downstream targets to regulate cell cycle exit in adult neurogenesis and oligodendrogenesis.

This study uses single-cell RNA sequencing to analyze SVZ stem cells across aging in mice, identifying distinct cell types and aging-related changes in stem cell behavior.

The paper analyzes 3'UTR changes during neuronal differentiation and in ASD, finding longer 3UTRs in ASD patients and a role for CPEB4 and APLP1 in APA regulation.