Author

Rodrigo Aguilar

Universidad Andrés BelloORCID 0000-0003-0410-5478Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biophysics· 1 Cancer Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Diego Leiva· 2 shared Marcelo Muñoz-González· 2 shared Michelle Tobar-Lara· 2 shared Adriana Rojas· 1 shared Álvaro A. ElorzaiD· 1 shared Andrea MatamorosiD· 1 shared Andrew Acevedo· 1 shared Ankush SinghaliD· 1 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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2 shared papersCancer Biology

Diego Leiva

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Cancer BiologybioRxivPreprintAug 28, 2026

MALAT1 Levels Are Elevated in Thyroid Tumors from Chilean Patients with Lymphatic Infiltration and Are Linked to Metabolic Reprogramming

Michelle Tobar-Lara, Andrea Matamoros, Marcelo Muñoz-González…·Rodrigo Aguilar

The paper examines MALAT1 levels in thyroid tumors from Chilean patients, finding a correlation with lymphatic infiltration and a link to mitochondrial quality control rather than direct metabolic reprogramming.

DOI 10.64898/2025.12.23.696116

humanbulk RNA-seq

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Molecular BiologyInternational Journal of Biological MacromoleculesPeer-reviewedAug 25, 2026

Deletion of the MALAT1 RNA 3' end Promotes Transcript Decay and Inhibits Proliferation in Gastric and Breast Cancer Cells

Aramis Cortes-Arias, Valeria Valdes, Marcelo Muñoz-González…·Rodrigo Aguilar

This study shows that deleting the 3' end of MALAT1 RNA reduces its stability and inhibits cancer cell proliferation in gastric and breast cancer models.

DOI 10.1016/j.ijbiomac.2026.154181

humanexperimental assay

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BiophysicsCommunications BiologyPeer-reviewedMar 23, 2026

Cleavage region organizes the structural architecture of the B2 SINE ribozyme

Ankush Singhal, Tyler Mrozowich, Carlos Rivera-López…·Karissa Y. Sanbonmatsu

The paper determines the structural ensemble-to-function relations of the B2 SINE ribozyme using RNA chemical probing, X-ray scattering, and modeling, showing cleavage site dependency on its structure and function.

1 citation

proteomicsexperimental assay

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