Author

Osman Doluca

İzmir University of EconomicsORCID 0000-0003-0412-6148Unclaimed ORCID profile · follow to get notified of new preprints

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Osman Doluca1 paper

Biology Disciplines

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Bioinformatics· 2 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:gene regulatory network inference· 2 Organism:human· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Assay:ChIP-seq· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

Aslı KaramaniD· 1 shared Efe BegariD· 1 shared Elif Nur Firat‐KaralariD· 1 shared Ferhan YenisertiD· 1 shared Hüseyin Saygın PortakaliD· 1 shared Mustafa S PiriD· 1 shared Oktay I. KaplaniD· 1 shared Oliver E. BlacqueiD· 1 shared

Activity by Year

2023-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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1 shared paperBioinformatics

Aslı KaramanORCID

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3 papers

Recent·Most cited

Molecular BiologybioRxivPreprintSep 3, 2026

Identification of a SARS-CoV-2 Spike RNA-Cleaving DNAzyme and Optimization of Its AS1411 Chimera

Zehra Banu Ünlü, Hüseyin Saygın Portakal, Osman Doluca

The paper identifies and optimizes a SARS-CoV-2 Spike RNA-cleaving DNAzyme, showing that its linear arrangement with an aptamer enhances cellular activity.

DOI 10.64898/2026.09.01.748480

humanexperimental assay

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BioinformaticsbioRxivPreprintMay 8, 2026

QuadStack: Specialized convolutional blocks enable in vivo BG4-binding motif prediction and highlight discrepancies with in vitro G-quadruplexes.

Polen Nehir Ulaş, Osman Doluca

QuadStack predicts in vivo BG4-binding motifs using deep learning, showing better performance than in vitro-based predictors and revealing discrepancies in G4 sequence grammar.

DOI 10.64898/2026.05.06.723235

ChIP-seqdeep learning

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BioinformaticsbioRxivPreprintMar 31, 2023

CilioGenics: an integrated method and database for predicting novel ciliary genes

Mustafa S Pir, Ferhan Yenisert, Aslı Karaman…·Oktay I. Kaplan

CilioGenics integrates multiple methodologies to predict novel ciliary genes, identifying 256 new candidates with 31 experimentally validated.

1 citation

humanbulk RNA-seq

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