Elif Nur Firat‐Karalar

SatelliteQ quantifies centriolar satellites in 2D, 3D, and time-lapse images, revealing spatial and numerical changes linked to cellular states and disease.

This study identifies CCDC66 as an actin-microtubule crosslinker that couples microtubule targeting to focal adhesion turnover and migration, with implications for cancer progression.

This study identifies a hierarchical pathway for centriolar satellite assembly driven by PCM1 multimerization and reveals its functional importance in ciliary signaling.

This study identifies CSPP1 as a conserved regulator of multiciliogenesis and motile cilia function in vertebrates, showing its role in centriole amplification, basal body migration, and ciliary structure and function.

This study shows that Pml loss worsens NEK1-linked ALS, while Pml induction reduces disease symptoms by clearing Nek1t aggregates.

This study identifies Ccdc66 as a microtubule-stabilizing factor that regulates primary cilium stability, disassembly, and signaling in mouse epithelial cells.

CilioGenics integrates multiple methodologies to predict novel ciliary genes, identifying 256 new candidates with 31 experimentally validated.