Author

Maria Alexandra Brehm

University of SiegenORCID 0000-0003-0416-8233Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Caroline KörösyiD· 1 shared Jan LipfertiD· 1 shared Stefanie D. PritzliD· 1 shared Tobias Obser· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

4 top collaborators · 6 mutual co-author links

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1 shared paperBiophysics

Caroline KörösyORCID

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1 paper

Recent·Most cited

BiophysicsJournal of Molecular BiologyPeer-reviewedSep 21, 2026

Magnetic Tweezers Experiments Reveal Increased Mechanical Sensitivity of the F2561Y Mutant in Von Willebrand Factor

Caroline Körösy, Stefanie D. Pritzl, Tobias Obser…·Jan Lipfert

This study uses magnetic tweezers to show the F2561Y mutation in VWF lowers stem opening force and increases open conformations, explaining its prothrombotic effects.

DOI 10.1016/j.jmb.2026.170028

humanexperimental assay

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