BioinformaticsbioRxivPreprint
Reference-Based Library Construction Improves Performance in low-input Workflows
Joshua Charkow, Mahmoudreza Ghaznavi, Brendon Seale…·Hannes Luc Röst
The paper improves library construction for low-input proteomics by using reference samples, showing significant performance gains in both OpenSWATH and DIA-NN workflows.
DOI 10.64898/2026.04.29.721088