Author
Washington University in St. LouisORCID 0000-0003-0449-2164Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Shweta Tendulkar, Tong Wu, Amy M. Strickland…·Aaron DiAntonio
The paper investigates how partial disruption of lactate metabolism, specifically through LDHB loss, synergizes with ALS genetic risk factors to accelerate motor decline.
A. Joseph Bloom, Xianrong R. Mao, Amy M. Strickland…·Aaron DiAntonio
The paper identifies constitutively active SARM1 variants in ALS patients that induce neuropathy and neuroinflammation in mice.
Tong Wu, Jian Zhu, Amy M. Strickland…·Jeffrey Milbrandt
This study identifies neurotoxins that activate SARM1 by binding to its allosteric site, leading to NAD+ depletion and neuronal death.