Waqar Ahmad

This study shows that suppressing dihydrolipoamide dehydrogenase in C. elegens increases whole-body glucose and tau phosphorylation, with partial reversal of acetylcholine inhibition but not mobility impairment.

This study shows that suppressing the dld-1 gene in C. elegans reduces toxic A{beta} oligomers and improves AD-related phenotypes, but increases vulnerability to metabolic toxins.

This study shows glucose worsens Alzheimer's disease symptoms in C. elegans by promoting Aβ aggregation and tau hyperphosphorylation, and manipulating O-β-GlcNAcylation does not mitigate these effects.