Author

Ajantha S Abey

University of OxfordORCID 0000-0003-0484-8001Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Assay:electronic health records· 1

Frequent Co-Authors

Bryan NgiD· 2 shared Dayne A. Beccano-KellyiD· 2 shared Nora Bengoa‐VergnioryiD· 2 shared Richard Wade‐MartinsiD· 2 shared Charmaine LangiD· 1 shared Darragh Patrick O'BrieniD· 1 shared Féodora L. BertheratiD· 1 shared Humaira NooriD· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersNeuroscience

Bryan NgORCID

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2 papers

Recent·Most cited

Neurosciencenpj Parkinson s DiseasePeer-reviewedApr 12, 2024

Early striatal hyperexcitability in an in vitro human striatal microcircuit model carrying the Parkinson's GBA-N370S mutation

Quyen Do, Humaira Noor, Ricardo Márquez-Gómez…·Richard Wade‐Martins

This study shows that the GBA-N370S mutation causes early hyperexcitability in striatal neurons by reducing sodium and potassium currents, which can be mitigated by aging or PKA antagonism.

6 citations

humanelectronic health records

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NeuroscienceMolecular PsychiatryPeer-reviewedFeb 15, 2024

Tau depletion in human neurons mitigates A beta-driven toxicity

Bryan Ng, Jane Vowles, Féodora L. Bertherat…·Richard Wade‐Martins

This study shows that reducing tau in human neurons decreases A beta toxicity, supporting the role of tau in Alzheimer's disease mechanisms.

26 citationstop 2%

humanexperimental assay

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