Sungkwon Chung

This study uses MRI to measure responses of cultured cells and in vivo rat cortex to ionic solutions that modulate membrane potential, finding changes in T2 relaxation time and bound-to-free water proton ratio.

This study shows that cholesterol levels regulate APP localization in lipid rafts, affecting raft-dependent endocytosis and Aβ generation, suggesting a potential therapeutic target for Alzheimer's disease.