ImmunologyFrontiers in MicrobiologyPeer-reviewed
Unraveling the Dual Immunomodulatory and Immunogenic Roles of the Central Conserved Cysteine-Rich Region in Respiratory Syncytial Virus G Protein
Juan Gutman, Ana Luz Paletta, Federico Birnberg-Weiss…·Sebastián Esperante
This paper investigates how the redox state of the RSV G protein's central conserved cysteine-rich domain (CCD) influences its immunomodulatory and immunogenic properties, showing that monomeric forms suppress immune activation while oligomerization removes this effect.
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