Belinda P. P. Lay

This study shows that silencing cholinergic input from the basal forebrain to the infralimbic cortex during fear extinction prevents fear renewal, highlighting nicotinic signaling as a therapeutic target.

The paper shows that deleting a specific neuronal ensemble in the amygdala central nucleus impairs extinction memory retrieval and promotes behavioral restoration.

The paper shows that different fear extinction methods engage distinct cortical regions, with the infralimbic cortex involved in extinction via omission and the orbitofrontal cortex involved in extinction via overexpectation.