Bruce T. Hope

This study identifies Grin2c expression in mPFC neurons as a molecular component of cocaine-induced conditioned place preference engrams.

The paper identifies a unique mushroom spine morphology signature in rat nucleus accumbens core neurons selectively activated during cocaine relapse.

This study shows that heroin relapse triggered by drug cues persists for over a year in abstinent rats, indicating long-term vulnerability to opioid relapse.

The paper shows that distinct prelimbic cortex ensembles encode response execution and inhibition during different phases of operant learning in rats.

The paper identifies a unique transcriptional signature in NAc neuronal ensembles activated during alcohol memory retrieval, showing their role in relapse and potential as therapeutic targets.

This study shows that ventral subiculum neuronal ensembles are specifically involved in the incubation of oxycodone craving after voluntary abstinence, but not after forced abstinence or early abstinence.

The paper establishes a mouse model of incubation of palatable food craving and identifies brain-wide activation patterns using whole-brain activity mapping.

The paper shows that deleting a specific neuronal ensemble in the amygdala central nucleus impairs extinction memory retrieval and promotes behavioral restoration.

This study investigates DS-controlled incubation of cocaine craving in rats, finding that cocaine-seeking behavior increases over abstinence, unlike food-seeking behavior.