Christian Staerk

StabCell integrates clustering and marker detection in scRNA-seq to improve robustness and reduce false positives by assessing stability across subsampled data.

CleanFinder is a scalable framework for analyzing genome editing outcomes, enabling detailed genotyping and comparison across diverse edit types and contexts.

This paper investigates how polygenic risk scores (PRS) transfer between populations by simulating demographic changes and dominance coefficients, finding that recessive traits are more conserved.

This paper introduces an efficient boosting algorithm for polygenic risk scores, showing improved computational efficiency and prediction accuracy compared to existing methods.

The paper applies statistical learning methods to develop sparser polygenic models for LDL-cholesterol prediction using UK Biobank data, showing competitive performance compared to classical approaches.