Author

Sophia K. DeGeorgia

Washington University in St. LouisORCID 0000-0003-0539-0039Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Organism:zebrafish· 1

Frequent Co-Authors

Charles K. KaufmaniD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

1 paper

Recent·Most cited

Cancer BiologybioRxivPreprintDec 12, 2024

Specific SOX10 enhancer elements modulate phenotype plasticity and drug resistance in melanoma

Sophia K. DeGeorgia, Charles K. Kaufman

This study identifies SOX10 enhancer elements in melanoma that drive phenotype plasticity and drug resistance by modulating SOX10 expression and NTRK1 upregulation.

2 citations

zebrafishhuman

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