Author

Charles K. Kaufman

Washington University in St. LouisORCID 0000-0003-3122-1677Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2 Genomics· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1 Assay:proteomics· 1

Frequent Co-Authors

Abimbola OyedejiiD· 1 shared Anna P. ZaroviD· 1 shared Catherine M Newsom-StewartiD· 1 shared Dhaval P. BhattiD· 1 shared Gregory D. LongmoreiD· 1 shared Jacqueline L. MuddiD· 1 shared Michael B. MajoriD· 1 shared Paula M. GodoyiD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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1 shared paperGenomics

Abimbola OyedejiORCID

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3 papers

Recent·Most cited

Cancer BiologybioRxivPreprintSep 3, 2025

Mapping of the hSOX10 protein interactome in human melanoma

Catherine M Newsom-Stewart, Dhaval P. Bhatt, Michael B. Major, Charles K. Kaufman

The paper maps the hSOX10 protein interactome in human melanoma using miniTurbo biotinylation and mass spectrometry, identifying 847 candidate interactors and highlighting key functional pathways.

DOI 10.1101/2025.09.03.672723

humanproteomics

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Cancer BiologybioRxivPreprintDec 12, 2024

Specific SOX10 enhancer elements modulate phenotype plasticity and drug resistance in melanoma

Sophia K. DeGeorgia, Charles K. Kaufman

This study identifies SOX10 enhancer elements in melanoma that drive phenotype plasticity and drug resistance by modulating SOX10 expression and NTRK1 upregulation.

2 citations

zebrafishhuman

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GenomicsCommunications BiologyPeer-reviewedNov 29, 2023

Functional analysis of recurrent non-coding variants in human melanoma

Paula M. Godoy, Abimbola Oyedeji, Jacqueline L. Mudd…·Charles K. Kaufman

The paper identifies functional non-coding variants in melanoma, showing that CDC20 promoter variants reduce transcriptional activity and alter melanoma phenotypes.

5 citations

humanbulk RNA-seq

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