Leah Swartzrock

The paper identifies Neogenin-1 as a marker for myeloid-biased fetal HSCs and shows that lineage bias is established early and reinforced with age.

This study demonstrates that in utero hematopoietic stem cell transplantation (HSCT) without conditioning can effectively engraft donor cells in FA mouse models, achieving high donor chimerism and potentially offering a safe prenatal treatment for FA.