Yijun Sun

The paper maps subgingival microbiome states in 1,355 adults, identifying divergent dysbiosis trajectories linked to periodontitis and host factors.

This study identifies an adenosine-Gzmk axis that drives T cell aging and systemic inflammaging, showing that targeting it can reverse aging phenotypes and extend lifespan in mice.

The paper investigates the roles of RESC13 and RESC14 in kinetoplastid RNA editing across multiple transcripts, finding conserved and transcript-specific functions.

This paper introduces AsMac, an alignment-free method for metagenomics sequence comparison, showing improved performance on variable-length sequences and handling insertions/deletions.

The paper develops a computational approach to model cancer progression using static tumor samples and applies it to breast cancer data, revealing a linear, branching evolutionary model with subtype shifts during progression.

This paper introduces DeepType, a deep learning framework for breast cancer subtype classification, which outperforms existing methods by identifying more robust subtypes with fewer genes.