Author

Patricia I. Diaz

University at Buffalo, State University of New YorkORCID 0000-0002-9501-1145Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 3 Cell Biology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Research Focus:cell type annotation· 3 Assay:metagenomics· 3 Approach:statistical model· 3 Research Focus:clustering· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Approach:biophysical modeling· 1

Frequent Co-Authors

Matthew SmardziD· 3 shared Dam SohiD· 2 shared Haralampos HatzikirouiD· 2 shared Moemen HusseiniD· 2 shared Anilei HoareiD· 1 shared Anurag K. Singh· 1 shared Arnab BaruaiD· 1 shared Ashley K. MilesiD· 1 shared

Activity by Year

2025-2026 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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3 shared papersMicrobiology

Matthew SmardzORCID

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

A population-scale landscape of the subgingival microbiome reveals divergent routes to periodontal dysbiosis

Lu Li, Moemen Hussein, Karen L. Falkner, Robert J Genco, Yijun Sun, Jean Wactawski‐Wende, Michael Joseph Buck, Haralampos Hatzikirou, Patricia I. Diaz

The paper maps subgingival microbiome states in 1,355 adults, identifying divergent dysbiosis trajectories linked to periodontitis and host factors.

bioRxiv · Oct 23, 2026 · PreprintMicrobiology

Chemotherapy-Induced Oral Mucosal Injury Is Defined by p53 Activation, Cell Cycle Arrest and Diverse Epithelial Progenitor Dynamics

Pedro H F SILVA, Lei Li, Madison Muriel, Tara Brennan, Md Hasanuzzaman, Mariadela Demoura, Joleene Stampfer, Michele Sveinsson, Christos K Fountzilas, Jill E. Schabert, Anurag K. Singh, Jonathan Bard, Nicolas F. Schlecht, Laertis Ikonomou, Patricia I. Diaz

In 5-FU-treated mice, oral and intestinal epithelial atrophy stems from p53-linked cell cycle arrest, not apoptosis, while a chemoresistant AP-1/p53 basal cluster expands in tongue.

bioRxiv · Sep 11, 2026 · PreprintCell Biology✦ In-depth digest

Pervasive integrative and conjugative elements shape Porphyromonas gingivalis gene repertoires

Cole B. Matrishin, Elaine M. Haase, Ashley K. Miles, Stephanie Steimer, Dam Soh, Matthew Smardz, Patricia I. Diaz, Kathryn M. Kauffman

This paper identifies pervasive integrative and conjugative elements (ICEs) in Porphyromonas gingivalis genomes, showing they contribute to strain-level gene diversity and virulence.

bioRxiv · Aug 5, 2026 · PreprintMicrobiology

Ecological and Stochastic Determinants of the Growth and Persistence of the Oral Pathogen Porphyromonas gingivalis

Moemen Hussein, Arnab Barua, Mohammad Ameen Qasaimeh, Matthew Smardz, Patricia I. Diaz, Haralampos Hatzikirou

The paper identifies ecological and stochastic factors influencing the growth and persistence of Porphyromonas gingivalis using mathematical modeling and experimental data.

npj Systems Biology and Applications · Feb 26, 2026Peer-reviewedSystems Biology

The Impact of Serum on a Complex Synthetic Community Model of the Subgingival Microbiome

Lu Li, Matthew Smardz, Dam Soh, Philip David Marsh, Anilei Hoare, Patricia I. Diaz

This study uses a synthetic subgingival microbiome model to show that serum intensifies dysbiosis by promoting pathogen growth and altering metabolism.

bioRxiv · Oct 7, 2025 · PreprintMicrobiology