GenomicsbioRxivPreprint
Single-cell gene regulatory network analysis reveals new melanoma cell states and transition trajectories during phenotype switching
Jasper Wouters, Zeynep Kalender Atak, Liesbeth Minnoye…·Stein Aerts
The paper identifies an intermediate cell state in melanoma through single-cell RNA-seq and ATAC-seq, revealing a gene regulatory network that governs phenotype switching and potential therapeutic targets.