Young Hee Lee

The paper develops a normative framework to distinguish need and motivation in hypothalamic neurons using computational models and experimental paradigms, showing AgRP and LHLepR neurons encode need and motivation respectively.

This study shows that activating hypothalamic GABAergic neurons in macaques increases naturalistic eating behavior and food motivation, with specific effects on palatable food.

This paper describes a behavioral protocol to quantify food-seeking behaviors in mice by creating a food-hidden environment and measuring specific actions like navigation and digging.

This study identifies LHLepR neurons as key to food-seeking and evaluating behaviors, showing how hunger gates motivation through neural circuits.