Author

Hyeon-Gu Yeo

Korea Research Institute of Bioscience and BiotechnologyORCID 0000-0002-6600-6291Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2 Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:non-human primate· 2 Assay:CRISPR screen· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Jinyoung WoniD· 3 shared Junghyung ParkiD· 3 shared Chang‐Yeop JeoniD· 2 shared Jae‐Won HuhiD· 2 shared Keonwoo KimiD· 2 shared Kyung Seob LimiD· 2 shared Younghyun KimiD· 2 shared Youngjeon LeeiD· 2 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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3 shared papersNeuroscience

Jinyoung WonORCID

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3 papers

Recent·Most cited

BioengineeringMolecular Therapy — Nucleic AcidsPeer-reviewedJun 17, 2026

Optimizing twin prime editing components for scalable genome editing and therapy in spinocerebellar ataxia type 3

Lee Wha Gwon, Jung Bae Seong, Hyeon-Gu Yeo…·Seung Hwan Lee

This study optimizes twin prime editing components to improve genome editing efficiency and accuracy for therapeutic applications in spinocerebellar ataxia type 3.

DOI 10.1016/j.omtn.2026.102988

humanCRISPR screen

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NeurosciencebioRxivPreprintJun 11, 2023

Hypothalamic neuronal activation in primates drives naturalistic goal-directed eating behavior

Leslie Jaesun Ha, Hyeon-Gu Yeo, Yu Gyeong Kim…·Hyung Jin Choi

This study shows that activating hypothalamic GABAergic neurons in macaques increases naturalistic eating behavior and food motivation, with specific effects on palatable food.

1 citation

non-human primateexperimental assay

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NeuroscienceExperimental NeurobiologyPeer-reviewedOct 31, 2020

Impaired hand dexterity function in a non-human primate model with chronic Parkinson's disease

Jincheol Seo, Jinyoung Won, Keonwoo Kim…·Youngjeon Lee

This study evaluates hand dexterity function in a non-human primate Parkinson's disease model using a hand dexterity task and identifies correlations with tremor symptoms and dopamine transporter levels.

3 citations

non-human primateexperimental assay

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