Author

Paul W.M. Fedak

University of CalgaryORCID 0000-0003-0658-9381Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:imaging· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Aiswarya Madhu· 1 shared Alex J. BarkeriD· 1 shared Anshul S. JadliiD· 1 shared Arshroop Khaira· 1 shared Ashna Maredia· 1 shared Cameron D. A. Mackay· 1 shared Darrell D. BelkeiD· 1 shared David G. GuzzardiiD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperMolecular Biology

Aiswarya Madhu

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2 papers

Recent·Most cited

PhysiologybioRxivPreprintMar 23, 2025

Pharmacological inhibition of mitochondrial fission mitigates experimental thoracic aortic aneurysm

Anshul S. Jadli, Karina Pereira Gomes, Megan B. Meechem…·Vaibhav B. Patel

This study shows that inhibiting mitochondrial fission with mdivi-1 reduces thoracic aortic aneurysm (TAA) progression in mice by limiting vascular remodeling and inflammation.

DOI 10.1101/2025.03.23.644843

mouseimaging

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Molecular BiologyClinical EpigeneticsPeer-reviewedJul 28, 2021

Identification of Aorta-Specific DNA Methylation Patterns in Cell-Free DNA from Patients with Bicuspid Aortic Valve-Associated Aortopathy and Correlation with Aortic Wall Cell Death

Ashna Maredia, David G. Guzzardi, Mohammad Aleinati…·Steven C. Greenway

The paper identifies aorta-specific DNA methylation patterns in cell-free DNA from BAV-associated aortopathy patients and correlates them with aortic wall cell death.

14 citations

humanDNA methylation

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