PhysiologybioRxivPreprint
Pharmacological inhibition of mitochondrial fission mitigates experimental thoracic aortic aneurysm
Anshul S. Jadli, Karina Pereira Gomes, Megan B. Meechem…·Vaibhav B. Patel
This study shows that inhibiting mitochondrial fission with mdivi-1 reduces thoracic aortic aneurysm (TAA) progression in mice by limiting vascular remodeling and inflammation.