Author

Yaroslav A. Kainov

King's College LondonORCID 0000-0003-0664-9102Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:whole-genome sequencing· 2 Research Focus:cancer & tumor microenvironment· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Cristina DiasiD· 1 shared Eugene V. MakeyeviD· 1 shared Fursham HamidiD· 1 shared Tim HubbardiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

4 top collaborators · 2 mutual co-author links

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1 shared paperGenetic & Genomic Medicine

Cristina DiasORCID

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2 papers

Recent·Most cited

Genome-Wide Analysis Reveals a Role of 3'untranslated Region Variants Affecting Cleavage and Polyadenylation in Undiagnosed Rare Disorders

Yaroslav A. Kainov, Cristina Dias, Tim Hubbard

The paper identifies 3'UTR variants disrupting cleavage and polyadenylation as potential causes of undiagnosed rare disorders using deep learning on Genomics England data.

medRxiv · Feb 16, 2025 · PreprintGenetic & Genomic Medicine

Recurrent disruption of tumour suppressor genes in cancer by somatic mutations in cleavage and polyadenylation signals

Yaroslav A. Kainov, Fursham Hamid, Eugene V. Makeyev

This study identifies somatic mutations in cleavage and polyadenylation signals of tumour suppressor genes as a novel class of noncoding drivers in cancer.

eLife · Aug 22, 2024Peer-reviewedCancer Biology