Odd skipped-related 1 controls the pro-regenerative response of Fibro-Adipogenic Progenitors
Georgios Kotsaris, Taimoor H. Qazi, Christian H. Bucher, Hafsa Zahid, Sophie Pöhle‐Kronawitter, Vladimir Ugorets, William Jarassier, Stefan T. Börno, Bernd Timmermann, Claudia Giesecke‐Thiel, Aris N. Economides, Fabien Le Grand, Pedro Vallecillo-García, Petra I. Knaus, Sven Geißler, Sigmar Stricker
This study identifies Osr1 as essential for FAPs to support muscle regeneration by regulating communication with MuSCs and macrophages, and its loss leads to impaired regeneration and fibrosis.
npj Regenerative Medicine · Apr 5, 2023Peer-reviewedDevelopmental Biology