Christian H. Bucher

This study identifies a cortical niche-specific macrophage subset that drives early osteoclastogenesis in bone healing through spatial immune-stromal interactions in young mice.

This study shows that ECM viscoelastic properties in bone fracture hematoma influence macrophage polarization, with high stress relaxation time promoting pro-inflammatory and low promoting anti-inflammatory responses.

This paper shows that anisotropic hydrogel degradation patterns enhance hMSC alignment, mechanotransduction, and osteogenic differentiation compared to uniform materials.

This study identifies Osr1 as essential for FAPs to support muscle regeneration by regulating communication with MuSCs and macrophages, and its loss leads to impaired regeneration and fibrosis.