Molecular BiologybioRxivPreprint
CD248 activates TGF-β receptor I to promote vascular remodeling in pulmonary arterial hypertension
L. Jones, Hannah J. McIntire-Ray, Angela N. Morales…·Jarrod Wesley Barnes
This study identifies CD248 as a co-activator of TGF-β receptor I in pulmonary arterial hypertension, supporting anti-CD248 therapy as a targeted alternative to systemic TGF-β inhibition.