Author

Jarrod Wesley Barnes

University of Alabama at BirminghamORCID 0000-0002-1027-6591Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Organism:mouse· 2 Assay:proteomics· 2 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Andres J Gonzalez Coba· 2 shared Angela N. Morales· 2 shared Hannah J. McIntire-RayiD· 2 shared L. JonesiD· 2 shared Shia VangiD· 2 shared Aftab M. AhmadiD· 1 shared D XingiD· 1 shared Emma Lea MatthewsiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersMolecular Biology

Andres J Gonzalez Coba

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2 papers

Recent·Most cited

O-GlcNAc transferase regulates H2O2 production via p38 MAPK

L. Jones, Shia Vang, Hannah J. McIntire-Ray, Holly A. Petersen, Angela N. Morales, Rodríguez de la Rúa, Joshua Charles Anderson, Andres J Gonzalez Coba, S E Krick, Jarrod Wesley Barnes

This paper shows that OGT inhibition reduces TGF-β-induced p38 MAPK signaling and H2O2 production in lung fibroblasts through O-GlcNAcylation of p38 and p47phox.

bioRxiv · May 31, 2026 · PreprintMolecular Biology

CD248 activates TGF-β receptor I to promote vascular remodeling in pulmonary arterial hypertension

L. Jones, Hannah J. McIntire-Ray, Angela N. Morales, Shia Vang, Meghan June Hirsch, Andres J Gonzalez Coba, Emma Lea Matthews, Katherine L. Adriatico, Nicholas P Harris, Iram Zafar, D Xing, Vivian Y. Lin, Liping Tian, Gregory A. Payne, Aftab M. Ahmad, , Jarrod Wesley Barnes

This study identifies CD248 as a co-activator of TGF-β receptor I in pulmonary arterial hypertension, supporting anti-CD248 therapy as a targeted alternative to systemic TGF-β inhibition.

bioRxiv · Apr 29, 2026 · PreprintMolecular Biology