Heather M. Olson

CD248 activates TGF-β receptor I to promote vascular remodeling in pulmonary arterial hypertension

This study identifies CD248 as a co-activator of TGF-β receptor I in pulmonary arterial hypertension, supporting anti-CD248 therapy as a targeted alternative to systemic TGF-β inhibition.

Single-Cell Proteomics of Human Peripheral Blood Mononuclear Cells Exceeding 600 Cells per Day

This paper develops a high-throughput single-cell proteomic method for PBMCs, achieving 660 cells per day with 750 protein identifications per cell and identifying low-frequency cell types.

Phosphoproteomics unveils the signaling dynamics in neuronal cells stimulated with insulin and insulin-like growth factors

This study uses phosphoproteomics to analyze signaling dynamics in neuronal cells stimulated with insulin and IGFs, identifying key phosphorylation events and pathways involved in actin cytoskeletal regulation.

Activity-targeted metaproteomics uncovers rare syntrophic bacteria central to anaerobic community metabolism

The paper uses activity-targeted metaproteomics to study rare syntrophic bacteria in anaerobic communities, revealing their metabolic activity and a previously hypothesized oxidative glycine pathway.

A multimodal imaging approach for imaging the metabolic changes resulting from bronchopulmonary dysplasia

This paper presents a multimodal imaging approach to characterize metabolic changes in bronchopulmonary dysplasia, revealing altered lipid distributions and collagen remodeling in affected tissues.