NeuroscienceEBioMedicinePeer-reviewed
Translating Brain Anatomy and Disease from Mouse to Human in Latent Gene Expression Space
Chloé Jaroszynski, Mohammed Amer, Antoine Beauchamp…·Rogier B. Mars
This paper develops a VAE-based framework to translate mouse brain gene expression to human, showing that mouse disease models predict human Alzheimer's and Parkinson's patterns and identify the best mouse model for AD patients.