Author

Randolph K. Larsen

St. Jude Children's Research HospitalORCID 0000-0003-0727-0049Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Organism:bacteria (other)· 1 Research Focus:cell type annotation· 1 Assay:CUT&Tag· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Mark E. HatleyiD· 2 shared Aaron Poole· 1 shared Abigail E. McKnight· 1 shared Adam Rosenthal· 1 shared Amy Iverson· 1 shared Andrew T. NishimotoiD· 1 shared Anoop Murthy KavirayaniiD· 1 shared Bradley T. Stevens· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCancer Biology

Mark E. HatleyORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintOct 29, 2026

Myogenic and neural transcriptional circuitry determines PAX3::FOXO1 driven initiation of rhabdomyosarcoma

Bradley T. Stevens, Yang Zhang, Matthew R. Garcia…·Mark E. Hatley

This study uses a PAX3::FOXO1 inducible model to show P3F initiates ARMS transformation but is not required for maintaining proliferation or transcriptional programs.

DOI 10.64898/2026.10.27.761987

humanbulk RNA-seq

𝕏 PostBluesky

MicrobiologyCell Host & MicrobePeer-reviewedJul 22, 2026

RNA Quality Control Enables Antibiotic Tolerance

Andrew T. Nishimoto, Juan Cesar Federico Ortiz-Marquez, Michelle R. Scribner…·Jason W. Rosch

This study shows that RNA quality control through rny mutations enables antibiotic tolerance in Streptococcus pneumoniae by balancing transcriptional resilience and degradation.

1 citation

bacteria (other)bulk RNA-seq

𝕏 PostBluesky