Maximally Divergent Synonymous Gene Design with SIRIUS
Amirsadra Mohseni, Ian R. Wheeldon, Stefano Lonardi
SIRIUS generates maximally divergent DNA sequences for a given protein, reducing shared subsequences compared to existing methods.
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University of California, RiversideORCID 0000-0003-0735-6846Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
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Amirsadra Mohseni, Ian R. Wheeldon, Stefano Lonardi
SIRIUS generates maximally divergent DNA sequences for a given protein, reducing shared subsequences compared to existing methods.
Amirsadra Mohseni, Reyhane Ghorbani Nia, Aida Tafrishi…·Ian R. Wheeldon
ALLEGRO designs universal CRISPR sgRNA libraries targeting multiple fungal species, validated experimentally across three fungi and extended to others.
Adithya Ramesh, Varun Trivedi, Sang Cheon Lee…·Ian R. Wheeldon
acCRISPR improves CRISPR screen accuracy by correcting sgRNA activity, identifying essential genes in yeast under various conditions.