Author

Adithya Ramesh

University of California, RiversideORCID 0000-0001-5450-4667Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Synthetic Biology· 3

Signature Assays, Organisms & Methods

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Assay:CRISPR screen· 3 Organism:yeast· 3 Approach:deep learning· 2 Approach:statistical model· 2 Research Focus:variant effect prediction· 2 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Ian R. WheeldoniD· 3 shared Cory Schwartz· 2 shared Sang Cheon LeeiD· 2 shared Stefano LonardiiD· 2 shared Varun TrivediiD· 2 shared Aida Tafrishi· 1 shared Alexander NguyeniD· 1 shared Amirsadra MohseniiD· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersSynthetic Biology

Ian R. WheeldonORCID

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3 papers

Recent·Most cited

Synthetic BiologybioRxivPreprintJun 20, 2024

Optimized genome-wide CRISPR screening enables rapid engineering of growth-based phenotypes in Yarrowia lipolytica

Nicholas R. Robertson, Varun Trivedi, Brian Lupish…·Ian R. Wheeldon

The paper designs a high-activity CRISPR sgRNA library for Yarrowia lipolytica and uses it to identify genes involved in acetate and hydrocarbon tolerance.

4 citations

yeastCRISPR screen

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Synthetic BiologyCommunications BiologyPeer-reviewedJun 8, 2023

acCRISPR: An activity-correction method for improving the accuracy of CRISPR screens

Adithya Ramesh, Varun Trivedi, Sang Cheon Lee…·Ian R. Wheeldon

acCRISPR improves CRISPR screen accuracy by correcting sgRNA activity, identifying essential genes in yeast under various conditions.

11 citations

yeastCRISPR screen

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Synthetic BiologyNature CommunicationsPeer-reviewedFeb 17, 2022

Genome-wide functional screens enable the prediction of high activity CRISPR-Cas9 and -Cas12a guides in Yarrowia lipolytica

Dipankar Ranjan Baisya, Adithya Ramesh, Cory Schwartz…·Ian R. Wheeldon

The paper develops DeepGuide, a deep learning model to predict high activity CRISPR-Cas9 and -Cas12a guides in Yarrowia lipolytica using genome-wide functional screens.

60 citations

yeastCRISPR screen

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