Robert H. Cichewicz

This study identifies a mutation in PfAQP and duplication of superoxide dismutase genes as mechanisms of resistance to cryptosporin in Plasmodium falciparum.

The paper assesses how fungal selection methods and environment-mimicking culture conditions affect the diversity of natural product libraries.

This paper develops a method to reduce natural product library size using mass spectrometry spectral similarity, minimizing bioactive loss and enabling faster, cheaper drug discovery.