Author

Wenqi Li

Children's Medical CenterORCID 0000-0003-0751-2968Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:cell-cell communication· 1 Approach:experimental assay· 1

Frequent Co-Authors

Amelle ShillingtoniD· 2 shared Feng GuoiD· 2 shared Jason H. TchieuiD· 2 shared Xuyao ChangiD· 2 shared Cindy HuynhiD· 1 shared Constantinos ChronisiD· 1 shared Craig A. EricksoniD· 1 shared Elena AlbizzatiiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersNeuroscience

Amelle ShillingtonORCID

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2 papers

Recent·Most cited

NeurosciencebioRxivPreprintJun 19, 2026

Selective vulnerability of excitatory cortical neurons to ZMYND11 loss reveals cell-type-specific mechanisms of neurodevelopmental disorder risk

Xuyao Chang, Megan McKinley, Wenqi Li…·Jason H. Tchieu

The paper shows that ZMYND11 loss selectively affects excitatory cortical neurons, causing hyperexcitability and molecular changes, while inhibitory neurons are less affected, revealing cell-type-specific mechanisms in neurodevelopmental disorders.

DOI 10.64898/2026.06.16.732737

humanbulk RNA-seq

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NeuroscienceNature CommunicationsPeer-reviewedOct 9, 2025

ZMYND11 Functions in Bimodal Regulation of Latent Genes and Brain-like Splicing to Safeguard Corticogenesis

Xuyao Chang, Wenqi Li, Satoshi Matsui…·Jason H. Tchieu

This study investigates the role of ZMYND11 in neurodevelopment by analyzing its effects on cortical neural stem cells and splicing regulation in ASD risk factors.

6 citations

humanbulk RNA-seq

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