Eleonora Centofante

This study investigates the roles of anterior cingulate cortex (aCC) and ventro-medial prefrontal cortex (vmPFC) in the consolidation and recall of remote spatial memories using optogenetic manipulations in mice.

The paper compares neural activity patterns in the hippocampus after massed and distributed spatial training using c-Fos expression and machine learning.

The paper shows that distributed training engages the dorsolateral striatum more than massed training, and optogenetic stimulation of this region can enhance massed training's robustness to match distributed training.