Author

Clara L. Frazier

University of Wisconsin–MadisonORCID 0000-0003-0765-4827Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Organism:E. coli· 1 Approach:experimental assay· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

Amy M. WeeksiD· 1 shared Debashrito DebiD· 1 shared Umasankar Mondal· 1 shared William E. LeiteriD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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4 top collaborators · 6 mutual co-author links

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1 shared paperBiochemistry

Amy M. WeeksORCID

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1 paper

Recent·Most cited

BiochemistryNature ChemistryPeer-reviewedJul 18, 2025

Engineered reactivity of a bacterial E1-like enzyme enables ATP-driven modification of protein C termini

Clara L. Frazier, Debashrito Deb, William E. Leiter…·Amy M. Weeks

The paper develops an ATP-driven platform for C-terminal protein modification using a bacterial E1-like enzyme, enabling precise bioconjugation with diverse functional groups.

7 citations

E. coliproteomics

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