Amy M. Weeks

This study uses phage-assisted evolution to improve enzymes for noncanonical tyrosine biosynthesis in E. coli, increasing production of specific derivatives.

The paper develops a method to profile phosphatase and phospholyase specificity using phosphoproteome-derived peptide libraries and mass spectrometry, revealing sequence preferences and enzyme selectivity.

This study demonstrates the use of engineered halogenase RebH variants to brominate peptides, enabling Suzuki-Miyaura coupling for functional group installation and biological activity tuning.

The paper shows that dynamic UFMylation maintains cellular fitness by coordinating multi-organelle proteostasis through alanine-dependent mechanisms.

The paper identifies hookworm genes upregulated by the host immune system, focusing on intestinal-expressed genes in A. ceylanicum and their potential roles in immune evasion.

The paper describes a self-organizing circuit in Podophrya collini that optimizes predatory trap structure through adaptive scaling of tentacle number and length.

The paper develops an ATP-driven platform for C-terminal protein modification using a bacterial E1-like enzyme, enabling precise bioconjugation with diverse functional groups.