BiochemistrybioRxivPreprint
Aggregation of HAPLN2, a component of the perinodal extracellular matrix, is a hallmark of physiological brain aging in mice
Ayaka Watanabe, Shoshiro Hirayama, Itsuki Kominato…·Shigeo Murata
This study identifies HAPLN2 aggregation as a feature of brain aging in mice, linking it to microglial activation and potential brain inflammation.
DOI 10.1101/2025.01.09.632092