Author

W. Matthew Petroll

The University of Texas Southwestern Medical CenterORCID 0000-0003-0795-4539Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:mouse· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

David W. SchmidtkeiD· 2 shared Krithika S. IyeriD· 2 shared Victor D. VarneriD· 2 shared Daniel P. Maruri· 1 shared Kara PooleiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 9 mutual co-author links

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2 shared papersBioengineering

David W. SchmidtkeORCID

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2 papers

Recent·Most cited

BioengineeringInvestigative Ophthalmology & Visual SciencePeer-reviewedMar 12, 2025

Corneal keratocytes, fibroblasts, and myofibroblasts exhibit distinct transcriptional profiles in vitro

Kara Poole, Krithika S. Iyer, David W. Schmidtke…·Victor D. Varner

This study identifies distinct transcriptional profiles of cultured corneal keratocytes, fibroblasts, and myofibroblasts, revealing genes and pathways involved in their differentiation and potential therapeutic targets.

13 citationstop 1%

bulk RNA-seqstatistical model

𝕏 PostBluesky

BioengineeringbioRxivPreprintFeb 29, 2024

Treatment with both TGF-β1 and PDGF-BB disrupts the stiffness-dependent myofibroblast differentiation of corneal keratocytes

Krithika S. Iyer, Daniel P. Maruri, David W. Schmidtke…·Victor D. Varner

This study shows that treatment with both TGF-β1 and PDGF-BB disrupts stiffness-dependent myofibroblast differentiation of corneal keratocytes, decoupling molecular markers from contractile behavior.

2 citations

mouseproteomics

𝕏 PostBluesky